Leptin May Help Type 1 Diabetics
UT Southwestern Medical Center has set up a clinical study to determine if Leptin which is produced by fat cells in the body will help type 1 diabetics gain better control over their diabetes.
Phase 1 Study
In the phase 1 part of clinical study researchers will be using metreleptin, in is a slightly modified form. "Leptin has been very effective in improving diabetes in patients with lipodystrophies who have extreme lack of body fat, and recently leptin therapy has helped improve blood sugar control in animal models of type 1 diabetes," said Dr. Abhimanyu Garg, professor of internal medicine and principal investigator of the trial. "Although we have no assurances that this will work in humans, we hope that the addition of leptin will be beneficial to patients with type 1 diabetes."
The study’s goal is evaluate the tolerance and safety in type 1 diabetics. Leptin will be added to the human subjects insulin twice a day for a five month period. The clinical trial will last for seven months.
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